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Acantosis nigricans y linfoma no Hodgkin: presentación de un caso / Acanthosis nigricans and non-Hodgkin’s lymphoma: a case presentation
Junco Bonet, Miguel Damián; Larquin Comet, José Ignácio.
  • Junco Bonet, Miguel Damián; Hospital Universitario Manuel Ascunce Doménech. Camagüey. CU
  • Larquin Comet, José Ignácio; Hospital Universitario Manuel Ascunce Doménech. Camagüey. CU
Arch. méd. Camaguey ; 18(2): 200-208, feb.-abr. 2014.
Article in Spanish | LILACS | ID: lil-768026
RESUMEN
La acantosis nigricans fue la primera dermatosis en la que se reconoció un carácter paraneoplásico. La característica sobresaliente es la hiperpigmentación simétrica y el engrosamiento aterciopelado de la piel. Se sugiere que algún factor producido por el tumor estimula el crecimiento epidérmico.

Objetivo:

presentar un caso poco frecuente de un paciente con el diagnóstico de linfoma no Hodgkin y acantosis nigricans.Caso clínico se presenta el caso de un paciente masculino de 62 años de edad con antecedentes de hipertensión arterial que un año previo a su ingreso manifestó cambios en la coloración de la piel, dermatosis generalizada, hiperpigmentación e hiperqueratosis en las palmas de las manos y el cuello.

Conclusiones:

el tumor más frecuente asociado con acantosis es el adenocarcinoma abdominal en 90 por ciento de los casos, entre los cuales 64 a 69 por ciento son de origen gástrico; el resto (10 por ciento ) se asocian con cáncer no digestivo; linfoma de Hodgkin, micosis fungoide, cáncer de esófago, próstata y tiroides. En el linfoma no Hodgkin su asociación es considerada muy rara y son pocos los casos reportados en la bibliografía...
ABSTRACT
Acanthosis nigricans was the first dermatosis in which a paraneoplastic nature was identified. The most significant feature is symmetrical hyperpigmentation and velvety thickening of the skin. It is suggested that any factor produced by the tumor stimulates the epidermal growth.

Objective:

to present the infrequent case of a patient diagnosed with non-Hodgkin’s lymphoma and acanthosis nigricans.Clinical case the case of a sixty-two-year-old male patient with a personal history of high blood pressure is presented. A year before his admission the patient presented changes in the coloration of the skin, widespread dermatosis, hyperpigmentation and hyperkeratosis in the hands and neck.

Conclusions:

the most frequent tumor associated to acanthosis was abdominal adenocarcinoma, found in the 90 percent of the cases; among them a 64 to 69 percent were of gastric origin; the rest of the cases (10 percent) were associated to non-digestive cancer, Hodgkin’s lymphoma, mycosis fungoides, esophagus cancer, prostate cancer, and thyroid cancer. In relation to Hodgkin’s lymphoma, the association is considered as rare, and there are just a few cases reported in the bibliography...
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Paraneoplastic Syndromes / Lymphoma, Non-Hodgkin / Acanthosis Nigricans Type of study: Prognostic study Limits: Humans Language: Spanish Journal: Arch. méd. Camaguey Journal subject: Medicine Year: 2014 Type: Article Affiliation country: Cuba Institution/Affiliation country: Hospital Universitario Manuel Ascunce Doménech/CU

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Full text: Available Index: LILACS (Americas) Main subject: Paraneoplastic Syndromes / Lymphoma, Non-Hodgkin / Acanthosis Nigricans Type of study: Prognostic study Limits: Humans Language: Spanish Journal: Arch. méd. Camaguey Journal subject: Medicine Year: 2014 Type: Article Affiliation country: Cuba Institution/Affiliation country: Hospital Universitario Manuel Ascunce Doménech/CU