Effects of REM sleep restriction during pregnancy on rodent maternal behavior
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
;
37(4): 303-309, Oct.-Dec. 2015. tab, graf
Article
in English
| LILACS
| ID: lil-770001
ABSTRACT
Objective:
To evaluate the effects of sleep restriction during pregnancy on maternal care and maternal aggression in a rodent model.Methods:
Twenty-three female Wistar rats were assigned to one of two groups control (n=12) or sleep restriction (n=11) during the entire pregnancy. At the fifth postpartum day, the animals were subjected to the resident-intruder paradigm and to the pup retrieval test.Results:
Sleep restriction during pregnancy had no direct effects on maternal care. Regarding aggressive behavior, defensive aggression was increased by sleep loss, with a lower responsiveness threshold to hostile environmental stimuli. Sleep deprivation during gestation also reduced self-grooming behavior.Conclusion:
Taking increased self-grooming as a behavioral correlate of anxiety in rodents, this study provides evidence that lactating dams were in a condition of reduced anxiety. From an adaptive perspective, this pattern of stress response may function to ensure proper maternal behavior, thereby guaranteeing the survival and viability of the litter. Under a translational perspective, the present article confronts the importance of biological and adaptive features to rodent maternal behavior with the relevance of sociocultural factors to the human mother-infant relationship and to the onset of postpartum depression.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Sleep Deprivation
/
Pregnancy
/
Maternal Behavior
Type of study:
Prognostic study
Limits:
Animals
/
Pregnancy
Language:
English
Journal:
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
Journal subject:
Psychiatry
Year:
2015
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Federal de São Paulo (UNIFESP)/BR
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