A 20-week program of resistance or concurrent exercise improves symptoms of schizophrenia: results of a blind, randomized controlled trial
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
;
37(4): 271-279, Oct.-Dec. 2015. tab, graf
Article
in English
| LILACS
| ID: lil-770006
ABSTRACT
Objective:
To evaluate the effects of 20 weeks of resistance and concurrent training on psychotic and depressive symptoms, quality of life outcomes, and serum IGF-1, IGFBP-3, and brain-derived neurotrophic factor (BDNF) concentrations in patients with schizophrenia.Methods:
In this blind, randomized controlled clinical trial, 34 patients with schizophrenia were assigned to one of three groups control (CTRL, n=13), resistance exercise (RESEX, n=12), or concurrent exercise (CONCEX, n=9). Symptoms, quality of life, strength, and other variables were assessed.Results:
A significant time-by-group interaction was found for the RESEX and CONCEX groups on the Positive and Negative Syndrome Scale (PANSS) total score for disease symptoms (p = 0.007), positive symptoms (p = 0.003), and on the arm extension one-repetition maximum (1RM) test (p = 0.016). In addition, significant improvements on negative symptoms (p = 0.027), on the role-physical domain of the Short Form-36 Health Survey (p = 0.019), and on the chest press 1RM test (p = 0.040) were observed in the RESEX group. No changes were observed for the other variables investigated.Conclusions:
In this sample of patients with schizophrenia, 20 weeks of resistance or concurrent exercise program improved disease symptoms, strength, and quality of life. ClinicalTrials.gov NCT01674543.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Schizophrenia
/
Exercise Therapy
/
Resistance Training
Type of study:
Controlled clinical trial
/
Diagnostic study
Limits:
Adolescent
/
Adult
/
Humans
/
Male
Language:
English
Journal:
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
Journal subject:
Psychiatry
Year:
2015
Type:
Article
/
Project document
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Federal de São Paulo (UNIFESP)/BR
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