Alternariol 9-methyl ether from the endophytic fungus Alternaria sp. Samif01 and its bioactivities
Braz. j. microbiol
;
47(1): 96-101, Jan.-Mar. 2016. tab, graf
Article
in English
| LILACS
| ID: lil-775130
ABSTRACT
Abstract One bioactive compound, identified as alternariol 9-methyl ether, was isolated from the crude extract of the endophytic fungus Alternaria sp. Samif01 residing in the roots of Salvia miltiorrhiza Bunge. Alternariol 9-methyl ether was active against bacteria with minimum inhibitory concentration values ranging from 25 to 75 µg/mL and median inhibitory concentration (IC50) values ranging from 16.00 to 38.27 µg/mL. The IC50 value of alternariol 9-methyl ether against spore germination of Magnaporthe oryzae was 87.18 µg/mL. Alternariol 9-methyl ether also showed antinematodal activity against Bursaphelenchus xylophilus and Caenorhabditis elegans with IC50 values of 98.17 µg/mL and 74.62 µg/mL, respectively. This work is the first report on alternariol 9-methyl ether and its biological activities from the endophytic fungus Alternaria sp. Samif01 derived from S. miltiorrhiza Bunge. The results indicate the potential of Alternaria sp. Samif01 as a source of alternariol 9-methyl ether and also support that alternariol 9-methyl ether is a natural compound with high potential bioactivity against microorganisms.
Full text:
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Index:
LILACS (Americas)
Main subject:
Alternaria
/
Endophytes
/
Lactones
/
Anti-Infective Agents
Limits:
Animals
Language:
English
Journal:
Braz. j. microbiol
Journal subject:
Microbiology
Year:
2016
Type:
Article
/
Project document
Affiliation country:
China
Institution/Affiliation country:
China Agricultural University/CN
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