The effect of prenatal exposure to 1800 MHz electromagnetic field on calcineurin and bone development in rats
Acta cir. bras
;
31(2): 74-83, Feb. 2016. tab, graf
Article
in English
| LILACS
| ID: lil-775567
ABSTRACT
PURPOSE:
To investigated the effects of exposure to an 1800 MHz electromagnetic field (EMF) on bone development during the prenatal period in rats.METHODS:
Pregnant rats in the experimental group were exposed to radiation for six, 12, and 24 hours daily for 20 days. No radiation was given to the pregnant rats in the control group. We distributed the newborn rats into four groups according to prenatal EMF exposure as follows Group 1 was not exposed to EMF; groups 2, 3, and 4 were exposed to EMF for six, 12, and 24 hours a day, respectively. The rats were evaluated at the end of the 60th day following birth.RESULTS:
Increasing the duration of EMF exposure during the prenatal period resulted in a significant reduction of resting cartilage levels and a significant increase in the number of apoptotic chondrocytes and myocytes. There was also a reduction in calcineurin activities in both bone and muscle tissues. We observed that the development of the femur, tibia, and ulna were negatively affected, especially with a daily EMF exposure of 24 hours.CONCLUSION:
Bone and muscle tissue development was negatively affected due to prenatal exposure to 1800 MHz radiofrequency electromagnetic field.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Prenatal Exposure Delayed Effects
/
Bone Development
/
Calcineurin
/
Electromagnetic Fields
Type of study:
Prognostic study
Limits:
Animals
/
Female
/
Humans
/
Male
Language:
English
Journal:
Acta cir. bras
Journal subject:
General Surgery
/
Procedimentos Cir£rgicos Operat¢rios
Year:
2016
Type:
Article
Affiliation country:
Turkey
Institution/Affiliation country:
Recep Tayyip Erdogan University/TR
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