Resultados a largo plazo en trasplante renal de donantes con criterios expandidos / Long-term outcomes with expanded criteria donors in kidney transplantation
Rev. méd. Chile
;
144(1): 22-29, ene. 2016. graf, tab
Article
in Spanish
| LILACS
| ID: lil-776971
ABSTRACT
Background:
Kidney transplantation of expanded criteria deceased donors (DCE) has become a common clinical practice. However, DCE outcomes are inferior compared to kidney transplants from standard criteria donors (DCS).Aim:
To evaluate intermediate and long-term outcomes of DCE transplanted patients. Material andMethods:
Cadaveric kidney transplants were evaluated using a retrospective cohort of eight consecutive years. Complications and long-term function of the transplant were assessed in DCE and DCS kidney recipients.Results:
Of 213 patients analyzed, 34 (16%) underwent DCE transplantation. DCS recipients spent more time on the waiting list for transplantation (p = 0.04). DCE recipients showed higher frequency of surgical complications (p = 0.04), vascular complications (p = 0.02), acute transplant rejection (p = 0.05), and hospitalizations (p = 0.01). Creatinine (mg/dL) in DCE and DCS recipients was 2.3 and 1.5 respectively at year one (p < 0.01) and 2.6 and 1.6 respectively at year five (p < 0.01). Graft survival in the DCE group was significantly lower at 5 years (61 and 89% respectively, p < 0.01).Conclusions:
DCE grafts are associated with lower survival, higher hospitalization rate and commonly develop surgical complications and rejections.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Kidney Transplantation
Type of study:
Etiology study
/
Observational study
/
Risk factors
Limits:
Adolescent
/
Humans
Country/Region as subject:
South America
/
Chile
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2016
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Hospital del Salvador/CL
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