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The Relationship between GRACE Score and Epicardial Fat Thickness in non-STEMI Patients / Relação entre Escore GRACE e Espessura da Gordura Epicárdica em Pacientes com IMSSST
Gul, Ilker; Zungur, Mustafa; Aykan, Ahmet Cagri; Gokdeniz, Teyyar; Kalaycioğlu, Ezgi; Turan, Turhan; Hatem, Engin; Boyaci, Faruk.
  • Gul, Ilker; Şifa University. Faculty of Medicine. Department of Cardiology. Izmir. TR
  • Zungur, Mustafa; Şifa University. Faculty of Medicine. Department of Cardiology. Izmir. TR
  • Aykan, Ahmet Cagri; Şifa University. Faculty of Medicine. Department of Cardiology. Izmir. TR
  • Gokdeniz, Teyyar; Şifa University. Faculty of Medicine. Department of Cardiology. Izmir. TR
  • Kalaycioğlu, Ezgi; Şifa University. Faculty of Medicine. Department of Cardiology. Izmir. TR
  • Turan, Turhan; Şifa University. Faculty of Medicine. Department of Cardiology. Izmir. TR
  • Hatem, Engin; Şifa University. Faculty of Medicine. Department of Cardiology. Izmir. TR
  • Boyaci, Faruk; Şifa University. Faculty of Medicine. Department of Cardiology. Izmir. TR
Arq. bras. cardiol ; 106(3): 194-200, Mar. 2016. tab, graf
Article in English | LILACS | ID: lil-777107
ABSTRACT
Abstract

Background:

GRACE risk score (GS) is a scoring system which has a prognostic significance in patients with non-ST segment elevation myocardial infarction (non-STEMI).

Objective:

The present study aimed to determine whether end-systolic or end-diastolic epicardial fat thickness (EFT) is more closely associated with high-risk non-STEMI patients according to the GS.

Methods:

We evaluated 207 patients who had non-STEMI beginning from October 2012 to February 2013, and 162 of them were included in the study (115 males, mean age 66.6 ± 12.8 years). End-systolic and end-diastolic EFTs were measured with echocardiographic methods. Patients with high in-hospital GS were categorized as the H-GS group (in hospital GS > 140), while other patients were categorized as the low-to-moderate risk group (LM-GS).

Results:

Systolic and diastolic blood pressures of H-GS patients were lower than those of LM-GS patients, and the average heart rate was higher in this group. End-systolic EFT and end-diastolic EFT were significantly higher in the H-GS group. The echocardiographic assessment of right and left ventricles showed significantly decreased ejection fraction in both ventricles in the H-GS group. The highest correlation was found between GS and end-diastolic EFT (r = 0.438).

Conclusion:

End-systolic and end-diastolic EFTs were found to be increased in the H-GS group. However, end-diastolic EFT and GS had better correlation than end-systolic EFT and GS.
RESUMO
Resumo Fundamento O escore de risco GRACE (SG) é um sistema com significado prognóstico para pacientes com infarto do miocárdio sem supradesnivelamento do segmento ST (IMSSST).

Objetivo:

Determinar se a espessura da gordura epicárdica (EGE) ao final da sístole ou da diástole é mais associada com pacientes de IMSSST de alto risco de acordo com o SG.

Métodos:

Este estudo avaliou 207 pacientes com IMSSST desde outubro de 2012 a fevereiro de 2013, sendo 162 deles incluídos no estudo (115 homens, idade média 66,6 ± 12,8 anos). Mediu-se a EGE ao final da sístole e da diástole com métodos ecocardiográficos. Pacientes com alto SG intra-hospitalar (SG > 140) foram classificados como grupo SG-A, enquanto os outros foram classificados como grupo de risco baixo-a-moderado (grupo SG-BM).

Resultados:

As pressões arteriais sistólica e diastólica dos pacientes SG-A foram mais baixas do que as dos pacientes SG-BM, sendo a frequência cardíaca média mais alta nesse grupo. A EGE ao final da sístole e a EGE ao final da diástole foram significativamente mais altas no grupo SG-A. A avaliação ecocardiográfica dos ventrículos direito e esquerdo mostrou fração de ejeção significativamente reduzida em ambos os ventrículos no grupo SG-A. Observou-se maior correlação entre SG e EGE ao final da diástole (r = 0,438).

Conclusão:

A EGE ao final da sístole e a EGE ao final da diástole mostraram-se aumentadas no grupo SG-A. Entretanto, a EGE ao final da diástole apresentou melhor correlação com o SG do que a EGE ao final da sístole.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Pericardium / Adipose Tissue / Acute Coronary Syndrome Type of study: Diagnostic study / Etiology study / Observational study / Prognostic study / Risk factors Limits: Aged / Aged80 / Female / Humans / Male Language: English Journal: Arq. bras. cardiol Journal subject: Cardiology Year: 2016 Type: Article Affiliation country: Turkey Institution/Affiliation country: Şifa University/TR

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Full text: Available Index: LILACS (Americas) Main subject: Pericardium / Adipose Tissue / Acute Coronary Syndrome Type of study: Diagnostic study / Etiology study / Observational study / Prognostic study / Risk factors Limits: Aged / Aged80 / Female / Humans / Male Language: English Journal: Arq. bras. cardiol Journal subject: Cardiology Year: 2016 Type: Article Affiliation country: Turkey Institution/Affiliation country: Şifa University/TR