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Adjunctive Hyperbaric Oxygen Therapy promotes successful healing in patients with refractory Crohn's disease
Feitosa, Marley Ribeiro; Féres Filho, Omar; Tamaki, Camila Mussolin; Perazzoli, Camila; Bernardes, Mário Vinícius Angelete Alvarez; Parra, Rogério Serafim; Rocha, José Joaquim Ribeiro da; Féres, Omar.
  • Feitosa, Marley Ribeiro; University of São Paulo. Ribeirão Preto Medical School. Department of Surgery and Anatomy. BR
  • Féres Filho, Omar; University of São Paulo. Ribeirão Preto Medical School. Department of Surgery and Anatomy. BR
  • Tamaki, Camila Mussolin; University of São Paulo. Ribeirão Preto Medical School. Department of Surgery and Anatomy. BR
  • Perazzoli, Camila; University of São Paulo. Ribeirão Preto Medical School. Department of Surgery and Anatomy. BR
  • Bernardes, Mário Vinícius Angelete Alvarez; University of São Paulo. Ribeirão Preto Medical School. Department of Surgery and Anatomy. BR
  • Parra, Rogério Serafim; University of São Paulo. Ribeirão Preto Medical School. Department of Surgery and Anatomy. BR
  • Rocha, José Joaquim Ribeiro da; University of São Paulo. Ribeirão Preto Medical School. Department of Surgery and Anatomy. BR
  • Féres, Omar; University of São Paulo. Ribeirão Preto Medical School. Department of Surgery and Anatomy. BR
Acta cir. bras ; 31(supl.1): 19-23, 2016. tab, graf
Article in English | LILACS | ID: lil-779764
ABSTRACT

PURPOSE:

To investigate de adjunctive effect of Hyperbaric Oxygen Therapy in a group of patients with refractory Crohn's disease.

METHODS:

A total of 29 subjects with refractory Crohn's disease were submitted to daily sessions of Hyperbaric Oxygen Therapy, in a 2800 Sechrist Monoplace Hyperbaric Chamber (Sechrist, USA) pressurized to 2.4 ATA. Each session lasted 2 hours. The endpoint was closure of enterocutaneous fistulas and complete healing of Pyoderma Gangrenosum and perineal Crohn's disease.

RESULTS:

A total of 829 HBOT sessions were performed and no complications were noted. Overall success rate was 76% (22 cases). Pyoderma Gangrenosum and enterocutaneous fistulas had the highest successful healing rates (100% and 91%, respectively). Perineal Crohn's disease healing rate was 65%.

CONCLUSION:

Adjunctive Hyperbaric Oxygen Therapy promoted satisfactory healing in a group of patients with refractory Crohn's disease.
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Full text: Available Index: LILACS (Americas) Main subject: Wound Healing / Crohn Disease / Intestinal Fistula / Pyoderma Gangrenosum / Hyperbaric Oxygenation Type of study: Observational study / Risk factors Limits: Adult / Aged / Child / Humans / Male Language: English Journal: Acta cir. bras Journal subject: General Surgery / Procedimentos Cir£rgicos Operat¢rios Year: 2016 Type: Article Affiliation country: Brazil Institution/Affiliation country: University of São Paulo/BR

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Full text: Available Index: LILACS (Americas) Main subject: Wound Healing / Crohn Disease / Intestinal Fistula / Pyoderma Gangrenosum / Hyperbaric Oxygenation Type of study: Observational study / Risk factors Limits: Adult / Aged / Child / Humans / Male Language: English Journal: Acta cir. bras Journal subject: General Surgery / Procedimentos Cir£rgicos Operat¢rios Year: 2016 Type: Article Affiliation country: Brazil Institution/Affiliation country: University of São Paulo/BR