Papulonodular secondary syphilis: a rare clinic presentation confirmed by serologic and histologic exams

ABSTRACT

Abstract Syphilis is a sexually transmitted disease caused by Treponema pallidum and divided into three stages according to the duration of the disease primary, secondary and tertiary. Secondary syphilis has diverse clinical presentations, such as papular-nodular lesions. This presentation is rare, with 15 cases reported in the literature over the past 20 years. We report a case of secondary syphilis with papular-nodular lesions in a healthy 63-year-old patient, who has presented treponema in immunohistochemical examination of the skin lesions.