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Choroidal changes in pre-eclampsia during pregnancy and the postpartum period: comparison with healthy pregnancy / Alterações da coroide na pré-eclâmpsia durante a gravidez e período pós-parto: comparação com a gravidez saudável
Duru, Necati; Ulusoy, Döndü Melek; Özköse, Ayşe; Ataş, Mustafa; Karatepe, Arzu Seyhan; Ataş, Fatma; Arifoğlu, Hasan Basri; Yılmaz, Uğur.
  • Duru, Necati; Kayseri Education and Research Hospital. Department of Ophthalmology. Kayseri. TR
  • Ulusoy, Döndü Melek; Kayseri Education and Research Hospital. Department of Ophthalmology. Kayseri. TR
  • Özköse, Ayşe; Kayseri Education and Research Hospital. Department of Ophthalmology. Kayseri. TR
  • Ataş, Mustafa; Kayseri Education and Research Hospital. Department of Ophthalmology. Kayseri. TR
  • Karatepe, Arzu Seyhan; Kayseri Education and Research Hospital. Department of Ophthalmology. Kayseri. TR
  • Ataş, Fatma; Kayseri Education and Research Hospital. Department of Ophthalmology. Kayseri. TR
  • Arifoğlu, Hasan Basri; Kayseri Education and Research Hospital. Department of Ophthalmology. Kayseri. TR
  • Yılmaz, Uğur; Kayseri Education and Research Hospital. Department of Ophthalmology. Kayseri. TR
Arq. bras. oftalmol ; 79(3): 143-146, tab, graf
Article in English | LILACS | ID: lil-787335
ABSTRACT
ABSTRACT

Purpose:

To investigate subfoveal choroidal thickness (SFCT) in patients with pre-eclampsia using enhanced depth imaging optical coherence tomography (EDI-OCT).

Methods:

A sample of 73 pregnant women was studied over 28 weeks of gestation. The sample was divided into two groups one comprising pre-eclamptic pregnant women (n=32), and the other comprising healthy pregnant women (n=41). The SFCT was determined for all patients using EDI-OCT during pregnancy and at the third month of the postpartum period.

Results:

The SFCTs in pre-eclamptic pregnant women were 351.97 ± 22.44 and 332.28 ± 20.32 µm during the pregnancy and postpartum periods (p<0.001), respectively, whereas these values in healthy pregnant women were 389.73 ± 49.64 and 329.78 ± 22.36 µm (p<0.001), respectively. During pregnancy SFCT in pre-eclamptic pregnant women was significantly thinner than that in healthy pregnant women (p<0.001). However, there was no statistically significant difference during the postpartum period (p=0.623).

Conclusions:

The results suggest that SFCT is significantly decreased in pre-eclamptic pregnant women than in healthy pregnant women, despite no statistically significant difference in SFCT existing between the groups during the postpartum period.
RESUMO
RESUMO

Objetivo:

Investigar espessura subfoveal coroidal (SFCT) em pacientes com pré-eclâmpsia usando imagens de tomografia de coerência óptica de profundidade otimizada (EDI-OCT).

Método:

Uma amostra de 73 mulheres grávidas foi estudado ao longo de 28 semanas de gestação. A amostra foi dividida em dois grupos um com mulheres grávidas com pré-eclâmpsia (n=32), o outro com as mulheres grávidas saudáveis (n=41). SFCT foi determinada em todos os pacientes utilizando EDI-OCT durante a gravidez e no terceiro mês do período pós-parto.

Resultados:

Os SFCTs em gestantes com pré-eclâmpsia foram 351,97 ± 22,44 µm e 332,28 ± 20,32 µm durante o período de gravidez e pós-parto (p<0,001), respectivamente. Estes valores em mulheres grávidas saudáveis foram 389,73 ± 49,64 µm e 329,78 ± 22,36 µm (p<0,001), respectivamente. Durante a gravidez o SFCT foi significantemente mais fino em mulheres com pré-eclâmpsia quando comparado com as mulheres saudáveis (p<0,001). No entanto, não houve diferença estatisticamente significante no período pós-parto (p=0,623).

Conclusões:

Os resultados sugerem que SFCT é significativamente mais fino em gestantes com pré-eclâmpsia do que nas mulheres grávidas saudáveis, apesar de não haver diferença estatisticamente significativa na SFCT entre os grupos durante o período pós-parto.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Pre-Eclampsia / Choroid / Postpartum Period / Fovea Centralis Type of study: Observational study / Prevalence study / Risk factors Limits: Adolescent / Adult / Female / Humans Language: English Journal: Arq. bras. oftalmol Journal subject: Ophthalmology Year: 2016 Type: Article Affiliation country: Turkey Institution/Affiliation country: Kayseri Education and Research Hospital/TR

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Full text: Available Index: LILACS (Americas) Main subject: Pre-Eclampsia / Choroid / Postpartum Period / Fovea Centralis Type of study: Observational study / Prevalence study / Risk factors Limits: Adolescent / Adult / Female / Humans Language: English Journal: Arq. bras. oftalmol Journal subject: Ophthalmology Year: 2016 Type: Article Affiliation country: Turkey Institution/Affiliation country: Kayseri Education and Research Hospital/TR