Your browser doesn't support javascript.
loading
Leucopatía reversible de la protuberancia: en paciente con SIDA y tratamiento retroviral / Pontine reversible leucopathy in an AIDS patient associated with highly active antiretroviral therapy (HAART): report of one case
Cartier, Luis; Matamala, José Manuel; Yáñez, Alonso.
  • Cartier, Luis; Universidad de Chile. Facultad de Medicina. Departamento de Ciencias Neurológicas Oriente. Santiago. CL
  • Matamala, José Manuel; Universidad de Chile. Facultad de Medicina. Departamento de Ciencias Neurológicas Oriente. Santiago. CL
  • Yáñez, Alonso; Universidad de Chile. Facultad de Medicina. Departamento de Ciencias Neurológicas Oriente. Santiago. CL
Rev. méd. Chile ; 144(5): 675-679, mayo 2016. ilus, tab
Article in Spanish | LILACS | ID: lil-791057
ABSTRACT
Posterior reversible encephalopathy (PRES) is a condition characterized by T2 and FLAIR hyperintensities in magnetic resonance imaging (MRI) studies, localized preferentially in the occipital-parietal white matter regions. Pathological MRI images located in midbrain, pons, medulla and spinal cord, that could be asymptomatic, were recently included in this entity. These images are interpreted as vasogenic edema, which is caused by arterial hypertension or eclampsia, neurotoxicity related to immunosuppressive agents or chemotherapy, among other causes. We report a 25 years old asymptomatic male with AIDS, with normal blood pressure who after initiating highly active antiretroviral therapy (HAART) reported vertigo. The MRI showed a central pontine T2 hyperintensity with diffusion restriction, which was interpreted as a central pontine myelinolysis (CPM), but the lack of motor symptoms made improbable a real demyelination of the pons. The follow-up MRI revealed complete regression of the images. To our knowledge, this case could be the second report of a reversible leucopathy of the pons in a patient with AIDS, were the MRI images also simulated a CPM. This report extends the knowledge around the variability of the pathogenic interpretation of CPM images and their association with HAART.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Acquired Immunodeficiency Syndrome / Antiretroviral Therapy, Highly Active / Posterior Leukoencephalopathy Syndrome Type of study: Risk factors Limits: Adult / Humans / Male Language: Spanish Journal: Rev. méd. Chile Journal subject: Medicine Year: 2016 Type: Article Affiliation country: Chile Institution/Affiliation country: Universidad de Chile/CL

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Index: LILACS (Americas) Main subject: Acquired Immunodeficiency Syndrome / Antiretroviral Therapy, Highly Active / Posterior Leukoencephalopathy Syndrome Type of study: Risk factors Limits: Adult / Humans / Male Language: Spanish Journal: Rev. méd. Chile Journal subject: Medicine Year: 2016 Type: Article Affiliation country: Chile Institution/Affiliation country: Universidad de Chile/CL