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Influence of bisphosphonates on Implantology - literature review
Nascimento, Bárbara Botolli do; Pimenta, Claudia Aline; Yamashita, Celso; Zielak, João Cesar; Deliberador, Tatiana Miranda; Scariot, Rafaela.
  • Nascimento, Bárbara Botolli do; Positivo University. Specialization in Implantology. Curitiba. BR
  • Pimenta, Claudia Aline; Positivo University. Specialization in Implantology. Curitiba. BR
  • Yamashita, Celso; Positivo University. Specialization in Implantology. Curitiba. BR
  • Zielak, João Cesar; Positivo University. Specialization in Implantology. Curitiba. BR
  • Deliberador, Tatiana Miranda; Positivo University. Specialization in Implantology. Curitiba. BR
  • Scariot, Rafaela; Positivo University. Specialization in Implantology. Curitiba. BR
RSBO (Impr.) ; 12(2): 209-215, Apr.-Jun. 2015. tab
Article in English | LILACS | ID: lil-792046
ABSTRACT

Introduction:

Oral rehabilitation with dental implants becomes limited in patients who make use of sodium bisphosphonate (BF), because this drug inhibits osteoclast activity and thus osteoblastic, fundamental steps to implant osseointegration. Furthermore, this drug can cause osteonecrosis of the jaw (OJ). The dentist has to fully know about this drug and its side effects, to differentiate it from other changes.

Objective:

This study aimed to review the literature on the influence of bisphosphonates on implant and to evaluate the possible complications resulting from prolonged use, providing subsidies to the dentist to prevent and recognize the patient with osteonecrosis of the jaws Literature review The BPs are a class of drugs used for the treatment of bone diseases such as osteoporosis, because their mechanism of action inhibits the function of osteoclast. However, these drugs may cause some side effects known as the OJ. Patients undergoing intravenous therapy are more likely to develop these changes than those undergoing oral therapy. OJ is characterized by painful symptoms, leaving the exposed bone in the oral cavity. There are several treatment strategies according to the clinical stage that the patient presents.

Conclusion:

The installation of dental implants in patients who make use of BPs presents risks, since this drug can cause OJ.

Full text: Available Index: LILACS (Americas) Language: English Journal: RSBO (Impr.) Journal subject: Dentistry Year: 2015 Type: Article Affiliation country: Brazil Institution/Affiliation country: Positivo University/BR

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Full text: Available Index: LILACS (Americas) Language: English Journal: RSBO (Impr.) Journal subject: Dentistry Year: 2015 Type: Article Affiliation country: Brazil Institution/Affiliation country: Positivo University/BR