Ergotismo por uso simultáneo de ergotamínico y terapia antirretroviral: Report of one case / Ergotism due to simultaneous use of ergot alkaloids and high activity antiretroviral therapy
Rev. méd. Chile
;
144(6): 807-812, jun. 2016. ilus, tab
Article
in Spanish
| LILACS
| ID: lil-793989
ABSTRACT
High activity antiretroviral therapy may exacerbate the activity of ergot alkaloids due to an inhibition of cytochrome P450. We report a 57 years old female with AIDS treated with lamivudine, zidovudine, atazanavir, ritonavir and cotrimoxazole presenting with ischemic signs in the four limbs. There was acrocyanosis and weak radial and ulnar pulses. A family member referred that the patient used ergot alkaloids for headaches. An ergotism due to the simultaneous use of ergot alkaloids and antiretroviral therapy was suspected. The latter was discontinued and intravenous nitroglycerin, nifedipine and pentoxifyline were started with good results.
Full text:
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Index:
LILACS (Americas)
Main subject:
Ergotism
/
Antiretroviral Therapy, Highly Active
/
Ergot Alkaloids
Type of study:
Diagnostic study
Limits:
Female
/
Humans
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2016
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Hospital San Juan de Dios/CL
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