Does an asymmetric lobe in digital rectal examination include any risk for prostate cancer? results of 1495 biopsies
Int. braz. j. urol
;
42(4): 704-709, July-Aug. 2016. tab, graf
Article
in English
| LILACS
| ID: lil-794675
ABSTRACT
ABSTRACT Introduction:
Despite the well-known findings related to malignity in DRE such as nodule and induration, asymmetry of prostatic lobes, seen relatively, were investigated in a few studies as a predictor of prostate cancer so that there is no universally expected conclusion about asymmetry. We aimed to compare cancer detection rate of normal, asymmetric or suspicious findings in DRE by using biopsy results. Materials andMethods:
Data of 1495 patients underwent prostate biopsy between 2006-2014 were searched retrospectively. Biopsy indications were abnormal DRE and or elevated PSA level(>4ng/mL). DRE findings were recorded as Group 1 Benign DRE, Group 2 Asymmetry and Group 3 Nodule/induration. Age, prostatic volume, biopsy results and PSA levels were recorded.Results:
Mean age, prostate volume and PSA level were 66.72, 55.98 cc and 18.61ng/ mL respectively. Overall cancer detection rate was 38.66 % (575 of 1495). PSA levels were similar in group 1 and 2 but significantly higher in group 3. Prostatic volume was similar in group 1 and 2 and significantly lower in Group 3. Malignity detection rate of group 1,2 and 3 were 28.93%, 34.89% and 55.99% respectively. Group 1 and 2 were similar (p=0.105) but 3 had more chance for cancer detection.Conclusion:
Nodule is the most important finding in DRE for cancer detection. Only an asymmetric prostate itself does not mean malignity.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Prostate
/
Prostatic Neoplasms
/
Prostate-Specific Antigen
/
Digital Rectal Examination
Type of study:
Diagnostic study
/
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Aged
/
Humans
/
Male
Language:
English
Journal:
Int. braz. j. urol
Journal subject:
Urology
Year:
2016
Type:
Article
Affiliation country:
Turkey
Institution/Affiliation country:
GATA Haydarpasa Teaching Hospital/TR
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