Genome-wide analyses of HTLV-1aD strains from Cape Verde, Africa
Mem. Inst. Oswaldo Cruz
;
111(9): 594-596, Sept. 2016. graf
Article
in English
| LILACS
| ID: lil-794725
ABSTRACT
We characterised and reported the first full-length genomes of Human T-cell Lymphotropic Virus Type 1 subgroup HTLV-1aD (CV21 and CV79). This subgroup is one of the major determinants of HTLV-1 infections in North and West Africa, and recombinant strains involving this subgroup have been recently demonstrated. The CV21 and CV79 strains from Cape Verde/Africa were characterised as pure HTLV-1aD genomes, comparative analyses including HTLV-1 subtypes and subgroups revealed HTLV-1aD signatures in the envelope, pol, and pX regions. These genomes provide original information that will contribute to further studies on HTLV-1a epidemiology and evolution.
Full text:
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Index:
LILACS (Americas)
Main subject:
Human T-lymphotropic virus 1
/
Genome-Wide Association Study
Limits:
Humans
Country/Region as subject:
Africa
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2016
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Fundação Oswaldo Cruz/BR
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