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Antibacterial activity of the Piper aduncum oil and dillapiole, its main constituent, against multidrug-resistant strains / Actividad antibacteriana del aceite de Piper aduncum y dillapiole, su componente principal, frente a cepas resistentes a múltiples fármacos
Brazão, Maria AngéLica B; Brazão, Fabio V; Maia, José Guilherme S; Monteiro, Marta C.
  • Brazão, Maria AngéLica B; Universidade Federal do Pará. Programa de Pós-Graduação em Ciências Farmacêuticas. Belém. BR
  • Brazão, Fabio V; Laboratório Ruth Brazão. Belém. BR
  • Maia, José Guilherme S; Universidade Federal do Pará. Programa de Pós-Graduação em Ciências Farmacêuticas. Belém. BR
  • Monteiro, Marta C; Universidade Federal do Pará. Programa de Pós-Graduação em Ciências Farmacêuticas. Belém. BR
Bol. latinoam. Caribe plantas med. aromát ; 13(6): 517-526, nov.2014. ilus, tab
Article in English | LILACS | ID: lil-795822
ABSTRACT
The study aimed to evaluate the bactericidal activity of oil essential and dillapiole from P. aduncum against standard and multidrug-resistant strains of Staphylococcus spp. The oil showed antimicrobial action against these strains, but better results were obtained for the standards strains of S. epidermidis and S. aureus, with MIC of 250 and 500 ug/mL, respectively. Dillapiolle was less effective than the oil against the same standard and multi-drug resistant strains (MIC =1000 ug/mL). However, when dillapiolle was tested in combination with myristicin, another component of the oil, it increased its bactericidal activity and showed a synergistic action...
RESUMEN
El objetivo del estudio fue evaluar la actividad bactericida de los aceites esenciales y dillapiole de P. aduncum contra cepas estándar y multirresistentes de Staphylococcus spp. El aceite mostró acción antimicrobiana frente a estas cepas, pero se obtuvo mejores resultados para las cepas de S. epidermidis y S. aureus, con MIC de 250 y 500 ug/ml, respectivamente. Dillapiolle fue menos eficaz que el aceite contra cepas estándar y multirresistentes (MIC = 1000 ug/ml). Sin embargo, cuando dillapiolle fue probado en combinación con la miristicina, otro componente del aceite, que aumentó su actividad bactericida y mostró una acción sinérgica...
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Oils, Volatile / Plant Extracts / Piper / Anti-Bacterial Agents Limits: Humans Language: English Journal: Bol. latinoam. Caribe plantas med. aromát Journal subject: Botany / Medicine / Plantas Medicinais / Terapias Complementares Year: 2014 Type: Article Affiliation country: Brazil Institution/Affiliation country: Laboratório Ruth Brazão/BR / Universidade Federal do Pará/BR

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Full text: Available Index: LILACS (Americas) Main subject: Oils, Volatile / Plant Extracts / Piper / Anti-Bacterial Agents Limits: Humans Language: English Journal: Bol. latinoam. Caribe plantas med. aromát Journal subject: Botany / Medicine / Plantas Medicinais / Terapias Complementares Year: 2014 Type: Article Affiliation country: Brazil Institution/Affiliation country: Laboratório Ruth Brazão/BR / Universidade Federal do Pará/BR