Evaluation of wound healing treated with latex derived from rubber trees and Aloe Vera extract in rats
Acta cir. bras
;
31(9): 570-577, Sept. 2016. tab, graf
Article
in English
| LILACS
| ID: lil-796000
ABSTRACT
ABSTRACT PURPOSE:
To compare the use of latex derivative and Aloe vera extract to wound healing.METHODS:
Twenty one rats were randomly divided into three groups and each one had a wound made by incision. The treatment consisted in derivative of latex (GL), Aloe vera extract (GA) and saline solution (GC). The wound area was measured on the 7th, 14th and 21st days and macroscopic and microscopic evaluation were done.RESULTS:
The comparison between the measurements of the wounds presented statistical difference in GC and GA from the 7th day of evaluation and GL from the 14th day. The extent of the wound was significantly smaller by the 7th day in GL. Histologically, in GL, the neovascularization was significant on the 7th, 14th and 21st days. On the 21st day the scar was large and little mature. In GA and GC, the findings were similar on the 7th, 14th and 21st days with a slight better organization of skin and collagen on the 21st in GA.CONCLUSIONS:
Statistical analysis did not allow for the definition of the best topical agent. The latex had the highest angiogenesis, but a possible foreign body granuloma. Aloe vera has revealed a healing process adequated temporally in histology.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Wound Healing
/
Plant Extracts
/
Hevea
/
Aloe
/
Latex
/
Phytotherapy
Limits:
Animals
Language:
English
Journal:
Acta cir. bras
Journal subject:
General Surgery
/
Procedimentos Cir£rgicos Operat¢rios
Year:
2016
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Pontificia Universidade Católica de Goiás/BR
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