Asymptomatic infection with American cutaneous leishmaniasis: epidemiological and immunological studies
Mem. Inst. Oswaldo Cruz
; 111(10): 599-604, Oct. 2016.
Article
in En
| LILACS
| ID: lil-796903
Responsible library:
BR1.1
ABSTRACT
American cutaneous leishmaniasis (ACL) is a major public health problem caused by vector-borne protozoan intracellular parasites from the genus Leishmania, subgenera Viannia and Leishmania. Asymptomatic infection is the most common outcome after Leishmania inoculation. There is incomplete knowledge of the biological processes explaining the absence of signs or symptoms in most cases while other cases present a variety of clinical findings. Most studies of asymptomatic infection have been conducted in areas of endemic visceral leishmaniasis. In contrast, asymptomatic ACL infection has been neglected. This review is focused on the following (1) epidemiological studies supporting the existence of asymptomatic ACL infection and (2) immunological studies conducted to understand the mechanisms responsible for controlling the parasite and avoiding tissue damage.
Key words
Full text:
1
Index:
LILACS
Main subject:
Leishmaniasis, Cutaneous
/
Asymptomatic Infections
Limits:
Humans
Country/Region as subject:
America central
Language:
En
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
MEDICINA TROPICAL
/
PARASITOLOGIA
Year:
2016
Type:
Article