Pancreatic involvement in murine Schistosomiasis

ABSTRACT

Pancreatic involvement during murine schistosomiasis is frequent (30 to 80%), heterogeneous, usually mild, but can occasionally be severe, characterized by granulomatous pancreatitis. After infection, pancreatic granulomas appear from day 50 on, with th most severe pancreatitis being demonstrable between days 90 and 100. Mice thus appear to be a useful model for study of the pathogenesis of Schistosoma mansoni-induced pancreatitis