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Segmento ST como indicador de recanalizaçäo arterial após terapêutica trombolítica no infarto do miocárdio / ST segment as an arterial recanalization indicator after thrombolytic therapy in acute myocardial infarction
Tranchesi Junior, Bernardino; Caramelli, Bruno; Gebara, Otávio Celso; Albuquerque, Cícero Piva; Bellotti, Giovanni; Jatene, Adib Domingos; Pileggi, Fúlvio.
  • Tranchesi Junior, Bernardino; s.af
  • Caramelli, Bruno; s.af
  • Gebara, Otávio Celso; s.af
  • Albuquerque, Cícero Piva; s.af
  • Bellotti, Giovanni; s.af
  • Jatene, Adib Domingos; s.af
  • Pileggi, Fúlvio; s.af
Arq. bras. cardiol ; 55(4): 233-236, out. 1990. tab
Article in Portuguese | LILACS | ID: lil-90626
RESUMO

Objetivo:

Avaliar a importância do segmento ST como indicador de recanalizaçäo da artéria em pacientes com infarto do miocárdio submetidos a terapêutica trombolítica por via venosa. Casuística e

Métodos:

Setenta e quatro pacientes (62 homens, média de idade 52,6 ñ 10 anos) com oclusäo da artéria relacionada ao infarto (ARI) antes da infusäo venosa "in bolus" de rt-PA em doses de 50, 60 e 70 mg. Após 90 minutos realizou-se nova angiografia e o estado da ARI foi relacionado ao comportamento do segmento ST antes e após o tratamento.

Resultados:

Cinqüenta e seis (75,6%) pacientes apresentaram normalizaçäo ou diminuiçäo do segmento ST (grupo I e II). Destes, em 47 notou-se recanalizaçäo da ARI. Dos demais 18 pacientes que näo apresentaram alteraçöes no segmento ST (grupo III), a ARI estava ocluída em 13 e recanalizada em cinco. O comportamento do segmento ST apresentou sensibilidade de 90,3% especificidade de 59,1%, valor preditivo positivo de 83,9% e valor preditivo negativo de 72,9%.

Conclusäo:

O segmento ST constitui importante indicador de recanalizaçäo ou näo da ARI após terapêutica trombolítica
ABSTRACT

Purpose:

To evaluate the importance of the segment ST in the identification of coronary recanalization in patients submitted to intravenous thrombolysis during acute myocardial infarction (MI). Patients and

Methods:

Seventy four patients with MI, 62 male with mean age of 52.6 ± 10 years. All patients had angiographically demonstrated occlusion of the infarct-related artery (IRA) before the thrombolytic treatment with intravenous in bolus infusion of 50 mg, 60 mg and 70 mg of rt-PA. The recanalization of the IRA was assessed 90 minutes later. The real status of the IRA in the angiograms was compared with the ST segment changes between the ECGs obtained before and after the thrombolytic therapy.

Results:

Fifty six (75.6% ) patients presented a significant reduction in the ST segment elevation (groups I and II). Of these, 47 possessed an openned IRA. From the 18 patients who did not show ST segment decrement (group III),13 had an occluded IRA, and 5 an openned one. The method presented sensitivity of 90.3% and a specificity of 59.1%, positive predictive value of 83.9% and negative predictive value of 72.2%.

Conclusions:

The ST segment is an important marker of coronary recanalization or not following intravenous thrombolytic therapy.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Thrombolytic Therapy / Coronary Vessels / Myocardial Infarction Limits: Adult / Female / Humans / Male Language: Portuguese Journal: Arq. bras. cardiol Journal subject: Cardiology Year: 1990 Type: Article

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Full text: Available Index: LILACS (Americas) Main subject: Thrombolytic Therapy / Coronary Vessels / Myocardial Infarction Limits: Adult / Female / Humans / Male Language: Portuguese Journal: Arq. bras. cardiol Journal subject: Cardiology Year: 1990 Type: Article