Involvement of beta-adrenergic receptors in the differential release of gonadotropins in acutely orchidectomized rats

ABSTRACT

To determine the diferential release fo gonadotropins in acutely orchidectomized rats, a single injection of the beta-adrenergic blocker Bornaprolol (FM 24) was administered to the animals and plasma FSH levels weredetermined. FM 24 produced low plasma FSH levels only when injected 16 h before starting the blood collection and had no effect on FSH levels at 0,30 and 46 h after its administration. However, it produced low LH plasma levels at 0,16 and 30 h after administration. These findings confirm that pituitary beta-adrenergic receptors are involved in plasma LH release and suggest that they could also be involved in the differential release of FSH/LH