Stress-induced desensitization of the cardiovascular response to noradrenaline in unanesthetized rats
Braz. j. med. biol. res
;
23(10): 1041-4, 1990. ilus
Article
in English
| LILACS
| ID: lil-91649
ABSTRACT
The present study was undertaken in order to analyse the effect of swimming stress on the blood pressure response to noradrenaline (NA) in unanesthetized rats. Suwimming induced a desensitization of the blood pressure response to NA which was not blocked by previnous animal treatment with prazosin (0.1 mg/Kg). However, rats submitted to stress showed increased sensitivity to the prazosin blocking effect. The results suggest that swimming-induced desensitization of the cardiovascular response to NA is mediated by alpha rather than beta-1 adrenoceptors
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Index:
LILACS (Americas)
Main subject:
Stress, Physiological
/
Blood Pressure
/
Epinephrine
/
Physical Exertion
Limits:
Animals
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
1990
Type:
Article
/
Congress and conference
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