Absence of zinc cytotoxicity: Effect of short-term zinc oral administration on rat gastric mucosa
Braz. j. med. biol. res
;
23(6/7): 519-23, 1990. ilus
Article
in English
| LILACS
| ID: lil-92196
RESUMO
Zinc ions have been reported to stabilize cellular membranes, protecting the gastric mucosa against a wide variety of ulcerative agents. The treatment with zinc sulfate intragastrically administered as one dose (20 mg/Kg body weight) daily for 30 consecutive days did not modify the normal aspect of rat gastric mucosa as observed by electron sanning microscopy. Furthermore, the X-ray microanalysis of the lysosome content performed on different gastric mucosa cells did not show the zinc element. These results suggest that zinc ion is a relatively nontoxic element for the rat gastric mucosa
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Index:
LILACS (Americas)
Main subject:
Sulfates
/
Zinc
/
Gastric Mucosa
Limits:
Animals
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
1990
Type:
Article
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