Development of a species-specific ELISA for Brazilian PIY-Viper venoms
Braz. j. med. biol. res
;
23(6/7): 585-8, 1990. ilus
Article
in English
| LILACS
| ID: lil-92208
RESUMO
Antigenic cross-reactivity between venoms of the genus Bothrops has been shown to be an extensive problem. However, some venom components are species-specific. In this study we have produced species-specific antivenoms against some members of the genus Bothrops. Monospecific rabbit antivenoms (IgG) were absorbed on venom affinity adsorbents. The species-specificity was tested by ELISA assays and immunoblots. The results of both assays showed complete species-specificity in some cases and highly increased species-specificity in others. These reagents can be used to determine the envenomating species in snake bite patients as an aid to improved serotherapy
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Index:
LILACS (Americas)
Main subject:
Immunoglobulin G
/
Enzyme-Linked Immunosorbent Assay
/
Antivenins
/
Crotalid Venoms
Limits:
Animals
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
1990
Type:
Article
/
Congress and conference
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