Disruptive effect of the mesencephalic reticular formation on tonic immobility in guinea pigs

Oliveira, L. Menescal de; Brentegani, M. R; Pereira, A. F; Hoffmann, A

Oliveira, L. Menescal de; Brentegani, M. R; Pereira, A. F; Hoffmann, A.

Braz. j. med. biol. res ; 23(8): 723-7, 1990. ilus

Article in English | LILACS | ID: lil-92330

ABSTRACT

ABSTRACT

Cholinergic stimulation of the mesencephalic reticular formation with carbachol impairs the induction of tonic immobility (TI) by restreining maneuvers and reduces the duration of immobility episodes in guiena pigs TI which permits the animal to evaluate the best6 time for escape. It is possible that this monitoring inolves cirucits and neurotransmitters other than the ascending cholinergic system origination in the mesencephalic reticular formation

Subject(s)

Guinea Pigs; Animals; Male; Behavior, Animal/drug effects; Carbachol/pharmacology; Cortical Synchronization/drug effects; Reticular Formation/physiology; Immobilization/physiology; Carbachol/administration & dosage; Microinjections

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Index: LILACS (Americas) Main subject: Reticular Formation / Behavior, Animal / Carbachol / Cortical Synchronization / Immobilization Limits: Animals Language: English Journal: Braz. j. med. biol. res Journal subject: Biology / Medicine Year: 1990 Type: Article / Congress and conference

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