The significance of phenotyping leukemias using monoclonal antibodies
Braz. j. med. biol. res
;
23(9): 763-72, 1990. ilus, tab
Article
in English
| LILACS
| ID: lil-92337
RESUMO
1. Acute leukemias have been defined as major types as of lymphoblastic and myeloblastic leuckemias according to morphological and cytochemical criteria. 2. The thecnical improvements and standardization of immunofluorescence and immunocytology staining methods have provied new insights for classifying these disorders on the basis of monoclonal antibodies. 3. The scheme used to describe normal lymphoid and myeloid differentiation, when also used to describe their malignant counterparts, provides a well-established model for the immunological classification of acute leukemias. 4. In this review article, we suggest some guidelines for performing a series of cytochemical reactions using immunological markers to ensure a reliable diagnosis of acute leukemia
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Index:
LILACS (Americas)
Main subject:
Leukemia, Myeloid, Acute
/
Leukemia, Lymphoid
/
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
/
Antibodies, Monoclonal
Type of study:
Practice guideline
/
Prognostic study
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
1990
Type:
Article
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