Histochemical and histological analysis of the leydig cells of cats treated with a supraphysiological dose of LH-RH analog
Braz. j. med. biol. res
;
23(9): 819-22, 1990. ilus, tab
Article
in English
| LILACS
| ID: lil-92402
RESUMO
An LH-RH analog (des-Gly10, [D-Trp6]-LH-RH A) was administered to adult male cats for 67 days (20 microng/Kg,sc) in order to study its inhibitory effects on the structure of Leydig cells, as deter,mined by histological and histochemical-morphometric techniques. Histological examination showed that LH-RH A promotes a decrease in the volume of the interstitial tissue. In addition, Leydig cell nuclei exhibited marked structural alterations. Morphometric analyses utilizing histochemistry of the enzyme 3-ß-hydroxysteroid dehydrogenase (3-ß-HOST-D) as a marker of Leydig cells also demostrated a signifcant decrease of the relative volume occupied by the Leydig cells isn the testis
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Index:
LILACS (Americas)
Main subject:
Testis
/
Gonadotropin-Releasing Hormone
/
3-Hydroxysteroid Dehydrogenases
/
Leydig Cells
Limits:
Animals
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
1990
Type:
Article
/
Congress and conference
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