Study on thermostabilizers for trivalent oral poliomyelitis vaccine
Mem. Inst. Oswaldo Cruz
;
85(3): 329-38, jul.-set. 1990. tab
Article
in English
| LILACS
| ID: lil-93596
ABSTRACT
Different formulations of trivalent oral poliomyelitis vaccine were tested, in order to obtain better thermostability, reduce corrosion of machinery and improve production costs. Magnesium chloride, sucrose, arginine and 199-Hank's medium were used in the formulations. The most appropriate formulation was a mixture of MgCl2 and arginine, which was highly thermostable, and had low production costs. The low corrosive formulation was rejected, due to low thermostability on storage
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Poliovirus Vaccine, Oral
Type of study:
Diagnostic study
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
1990
Type:
Article
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