Chromatographic purification of antivenoms and antitoxins

Dias, Waldely de Oliveira; Esteves, Maria Izabel; Furuta, Joana Akiro; Higashi, Hisako Gondo; Marcelino, José Roberto; Oishi, Nilza Yurimi; Prado, Sally Muller Alfonso; Tanaka, Anita Mitico; Ueda, Celina Maria Pompeo Mome; Raw, Isaias

Dias, Waldely de Oliveira; Esteves, Maria Izabel; Furuta, Joana Akiro; Higashi, Hisako Gondo; Marcelino, José Roberto; Oishi, Nilza Yurimi; Prado, Sally Muller Alfonso; Tanaka, Anita Mitico; Ueda, Celina Maria Pompeo Mome; Raw, Isaias.

Mem. Inst. Butantan ; 51(4): 195-203, 1989. ilus

Article in English | LILACS, SES-SP | ID: lil-93999

ABSTRACT

ABSTRACT

Commercial preparations of antivenoms and antitoxins produced in horses, that are essentially pure F (ab)2 immunoglobulin preparations, were submitted to ion-exchange chromatography. For anticrotalic, anti-bothropic and anti-tetanic sera it is possible to remove 40-60% of the inactive globulins

Subject(s)

Antitoxins; Antivenins; Chromatography

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Index: LILACS (Americas) Main subject: Antitoxins / Antivenins / Chromatography Language: English Journal: Mem. Inst. Butantan Year: 1989 Type: Article

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Index: LILACS (Americas) Main subject: Antitoxins / Antivenins / Chromatography Language: English Journal: Mem. Inst. Butantan Year: 1989 Type: Article