Age-associated changes of memory (CD45RO+) and naive (CD45R+) T cells
Braz. j. med. biol. res
;
24(3): 275-9, mar. 1991. tab
Article
in English
| LILACS
| ID: lil-99565
ABSTRACT
The total number of lymphocytes and the percentage of CD45RO+ (putative memory T cell) and CD45R+ (putative naive T cell) were determined in 15 cord blod samples, 66 healthy children ranging in a age from 1 to 18 years, 16 adults (23-59 years) and 16 aged individuals (60-96 years). The total number of lymphocytes decreased with age and reached the adult range in children to the adult group,white the percentage of CD45RO+ Tcells was low in cord blood and increased with age.No significant difference was observed between the adult and the aged groups for either lymphocyte subset. These data support the view that CD45RO+ and CD45R+ T-cell subsets represent maturational stages of T cells
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Index:
LILACS (Americas)
Main subject:
Aging
/
T-Lymphocytes
/
Antigens, CD
/
T-Lymphocyte Subsets
/
Histocompatibility Antigens
Type of study:
Risk factors
Limits:
Adolescent
/
Adult
/
Aged80
/
Child
/
Child, preschool
/
Humans
/
Infant
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
1991
Type:
Article
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