Extrahepatic biliary atresia and twinning
Rev. bras. pesqui. méd. biol
; Braz. j. med. biol. res;24(1): 67-71, jan.-mar. 1991. tab
Article
in En
| LILACS
| ID: lil-99583
Responsible library:
BR26.1
RESUMO
Four pairs of discordant twins were observed in a series of 237 extrahepatic biliary atresia patients ascertained in London. The twinning prevalence (1.7%) was as expedcted considering the ethnic composition of the sample. Out of a total of 17 other twin pairs reported in the literature only one was concordant for the disease. Since only 17 instances of familial cases have been described, the conclusion is that any influence of genetic factors in this condition is likely to be manifested indirectly, possibly in the form of increased susceptibility of the biliary epithelium to infectious or toxic agents
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Index:
LILACS
Main subject:
Biliary Atresia
/
Diseases in Twins
Type of study:
Risk_factors_studies
Limits:
Female
/
Humans
/
Infant
/
Male
/
Newborn
Language:
En
Journal:
Braz. j. med. biol. res
/
Rev. bras. pesqui. méd. biol
Journal subject:
BIOLOGIA
/
MEDICINA
Year:
1991
Type:
Article