Evaluation of anti-atherosclerotic and vasculoprotective effect of long acting nifedipine in patients after PTCA.
J Indian Med Assoc
;
2001 Sep; 99(9): 519-20, 522
Article
in English
| IMSEAR
| ID: sea-100293
ABSTRACT
The anti-atherosclerotic and vasculoprotective effect of long acting nifedipine (nicardia retard 20) was evaluated on patients undergoing percutaneous transluminal coronary angioplasty (PTCA). This was a randomised, controlled, prospective clinical trial. A total of 30 patients fulfilling inclusion criteria were divided randomly in 2 groups of 15 each. One group was given long acting nifedipine while other group did not receive long acting nifedipine. The rest of the treatment was similar for both the groups. Clinical and angiographic parameters were evaluated regularly for a period of one year. The group receiving long acting nifedipine showed 20% restenosis as against 33% in group not receiving long acting nifedipine. Thus, from this trial, it can be concluded that long acting nifedipine can reduce the progress of reocclusion and thus demonstrates the anti-atherosclerotic and vasculoprotective action.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Vasodilator Agents
/
Coronary Artery Disease
/
Female
/
Humans
/
Male
/
Calcium Channel Blockers
/
Nifedipine
/
Angioplasty, Balloon, Coronary
/
Survival Analysis
/
Delayed-Action Preparations
Type of study:
Controlled clinical trial
Language:
English
Journal:
J Indian Med Assoc
Year:
2001
Type:
Article
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