A study of changes in homocysteine levels during normal pregnancy and pre-eclampsia.
J Indian Med Assoc
;
2008 Aug; 106(8): 503-5
Article
in English
| IMSEAR
| ID: sea-102217
ABSTRACT
To find out changes in homocysteine levels that occur during normal pregnancy and pregnancy with pre-eclamptic toxaemia and also to find out correlation between homocysteine concentration and preeclamptic toxaemia a study was carried out among 90 women of which 30 were control which included normotensive non-pregnant women and the study group I comprised 30 pregnant normotensive women and the study group II comprised 30 pregnant women with pre-eclamptic toxaemia. Serum homocysteine was measured in all subjects using fluorescence polarisation immuno-assay. Control group had highest mean homocysteine levels while the study group I had least mean homocysteine levels (p < 0.001). Levels were significantly higher in subjects with BP > 146/100 mm Hg as compared to subjects with BP >140/90 and <146/100 mm Hg (p=0.017). There was significant difference between study group I and II at same gestational age. Hyperhomocysteinaemia was observed in pre-eclamptic females, also it was found that homocysteine levels were directly correlated with severity of pre-eclampsia.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Pre-Eclampsia
/
Female
/
Humans
/
Pregnancy
/
Case-Control Studies
/
Cross-Sectional Studies
/
Risk Factors
/
Adolescent
/
Perinatal Care
/
Adult
Type of study:
Etiology study
/
Observational study
/
Prevalence study
/
Risk factors
Language:
English
Journal:
J Indian Med Assoc
Year:
2008
Type:
Article
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