Effectiveness of bacillus of Calmette-Guerin (BCG) vaccination against tuberculous meningitis: a case-control study.
J Indian Med Assoc
;
1996 Sep; 94(9): 338-40
Article
in English
| IMSEAR
| ID: sea-102538
ABSTRACT
A hospital-based pair-matched case-control study was carried out at Government Medical College Hospital, Nagpur to estimate the effectiveness of bacillus of Calmette-Guerin (BCG) vaccination against tuberculous meningitis. The study included 92 cases of tuberculous meningitis in the age group of 0-12 years and equal number of controls, matched for age, sex and socio-economic status. The protective effectiveness and prevented fraction were higher for the subjects in the age group of 0-6 years, males and subjects from upper strata of socio-economic class. The overall vaccine effectiveness and prevented fraction were estimated to be 86.54% (70.38-93.88%) and 65.54% (39.22-80.64%) respectively. Results of this study thus indicated that BCG vaccination was highly effective against tuberculous meningitis and played significant role in its prevention, in this population.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Socioeconomic Factors
/
Tuberculosis, Meningeal
/
Female
/
Humans
/
Male
/
Infant, Newborn
/
BCG Vaccine
/
Case-Control Studies
/
Child
/
Child, Preschool
Type of study:
Observational study
Language:
English
Journal:
J Indian Med Assoc
Year:
1996
Type:
Article
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