Practical issues in geriatric psychopharmacology.
J Indian Med Assoc
;
1999 Apr; 97(4): 145-7
Article
in English
| IMSEAR
| ID: sea-102846
ABSTRACT
In summary, clinicians must consider multiple changes in the absorption, distribution, metabolism, and elimination of psychotropic drugs among older patients. Lower starting doses (often one-quarter to one-half the usual adult dose) is advisable, with slow dosing adjustments (no sooner than every 5 to 7 days) as needed. The time required to see steady-state therapeutic levels, or for elimination of most medications, are substantially longer in the elderly. One must consider the potential for drug-drug interactions, as well as anti-cholinergic or other side-effects, when prescribing a regimen. Changes should be made slowly, changing only one variable at a time, in order to achieve best results.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Psychotropic Drugs
/
Aged
/
Humans
/
Drug Administration Schedule
/
Dose-Response Relationship, Drug
/
Half-Life
/
Intestinal Absorption
/
Mental Disorders
Type of study:
Diagnostic study
Language:
English
Journal:
J Indian Med Assoc
Year:
1999
Type:
Article
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