Henoch-Schonlein syndrome in northern Indian children.
Indian Pediatr
;
1991 Oct; 28(10): 1153-7
Article
in English
| IMSEAR
| ID: sea-10379
ABSTRACT
In order to evaluate clinical features and renal pathological findings of Henoch-Schonlein syndrome (HSS) in northern Indian Children, we studied 47 such cases. The mean age at onset was 8.5 yr; sex ratio (MF) 2.61. The clinical features were purpuric rash (96%), abdominal pain (64%), Henoch-Schonlein nephritis (51%) and arthralgias (47%). Patients younger than 6 yr also showed urticarial rash or edema of scalp and extremities. Henoch-Schonlein nephritis (HSN) and abdominal symptoms were more common in older cases. The manifestations of HSN were asymptomatic hematuria and/or proteinuria (n = 15), acute nephritic syndrome (n = 6), and nephrotic syndrome (n = 3). The severity of clinical manifestations correlated with the renal pathologic findings. On follow up, 29% cases showed renal impairment. The prognosis was poor in patients with the acute nephritic or nephrotic syndrome and crescents in more than 50% glomeruli. Combination of clinical data and renal biopsy findings are important in assessing the long-term outcome in cases with HSN.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
IgA Vasculitis
/
Skin Diseases
/
Syndrome
/
Biopsy
/
Female
/
Humans
/
Male
/
Abdominal Pain
/
Child
/
Child, Preschool
Type of study:
Prognostic study
Country/Region as subject:
Asia
Language:
English
Journal:
Indian Pediatr
Year:
1991
Type:
Article
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