Genetics and bioinformatics of primary open angle glaucoma: an Indian perspective.
J Indian Med Assoc
;
2004 Dec; 102(12): 708, 710, 712 passim
Article
in English
| IMSEAR
| ID: sea-105885
ABSTRACT
Glaucoma is the second largest blinding disorder, after cataract, affecting about 67 million people worldwide. In India about 1.5 million people are blind due to glaucoma. Primary open angle glaucoma is the major sub-type of glaucoma affecting all ages and is genetically complex. Myocilin and optineurin are two different genes that have been implicated for primary open angle glaucoma. This review is focused on the studies being conducted in India on primary open angle glaucoma to identify the molecular defects and new directions undertaken using bioinformatic approaches towards a better understanding of the disease.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Vision Disorders
/
Chromosomes, Human, Pair 10
/
Humans
/
Glycoproteins
/
Glaucoma, Open-Angle
/
Blindness
/
Computational Biology
/
Cytoskeletal Proteins
/
Transcription Factor TFIIIA
/
Eye Proteins
Type of study:
Controlled clinical trial
/
Prognostic study
Country/Region as subject:
Asia
Language:
English
Journal:
J Indian Med Assoc
Year:
2004
Type:
Article
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