Humoral immunity status in patients with complicated pregnancies.

ABSTRACT

Serum immunoglobulin levels of 136 females inclusive of 20 non-pregnant volunteers, 21 normal pregnant mothers and 95 cases with complicated pregnancies were studied by radial immunodiffusion technique. Compared to normal western values immunoglobulin M levels were higher in 132 out of total 136 cases, immunoglobulin G levels were higher in 65 out of 95 cases with complicated pregnancies the majority of which included cases of eclampsia (16 cases), pre-eclamptic toxaemia (21 cases) and pre-eclamptic toxaemia with antepartum haemorrhage (11 cases) and immunoglobulin A levels were normal in all except 11 cases comprising normal pregnancy (1 case), eclampsia (3 cases), pre-eclamptic toxaemia (5 cases) and pregnancy with hypertension (2 cases).