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The effect of aspirin, paracetamol and analgin on pharmacokinetics of chloroquine.
Indian J Physiol Pharmacol ; 1993 Jul; 37(3): 229-31
Article in English | IMSEAR | ID: sea-106170
ABSTRACT
The effect of Aspirin, paracetamol and analgin on the kinetic profile of a single oral dose of chloroquine was studied in 8 healthy subjects. Aspirin did not alter the kinetic parameters of chloroquine whereas paracetamol and analgin significantly enhanced the Cmax and AUC0-alpha of chloroquine (P < 0.01, < 0.05 respectively).
Subject(s)
Full text: Available Index: IMSEAR (South-East Asia) Main subject: Humans / Male / Chloroquine / Aspirin / Dipyrone / Adult / Drug Interactions / Acetaminophen / Models, Biological Language: English Journal: Indian J Physiol Pharmacol Year: 1993 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Humans / Male / Chloroquine / Aspirin / Dipyrone / Adult / Drug Interactions / Acetaminophen / Models, Biological Language: English Journal: Indian J Physiol Pharmacol Year: 1993 Type: Article