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Effect of acute environmental heat stress on urinary water and electrolyte excretion in the rat.
Indian J Physiol Pharmacol ; 1988 Apr-Jun; 32(2): 126-31
Article in English | IMSEAR | ID: sea-106184
ABSTRACT
Plasma cortisol and urinary excretion of water, sodium, potassium, calcium and magnesium have been studied in the rat after application of heat stress. There was a significant increase in plasma cortisol level after exposure to heat. During heat stress complete cessation of urine formation was observed. In the next 30 min there was statistically significant increase in the urinary excretion of water, sodium and calcium but not of potassium and magnesium. Urinary calcium/magnesium ratio was also significantly elevated. The increase in urinary water and electrolyte excretion seemed to be mediated through prostaglandins since it could be abolished by administration of indomethacin prior to the application of heat stress. On the basis of these results, the possible role of heat stress in the genesis of urolithiasis has been discussed.
Subject(s)
Full text: Available Index: IMSEAR (South-East Asia) Main subject: Rats / Stress, Physiological / Urine / Body Water / Female / Hydrocortisone / Urinary Calculi / Electrolytes / Hot Temperature / Animals Language: English Journal: Indian J Physiol Pharmacol Year: 1988 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Rats / Stress, Physiological / Urine / Body Water / Female / Hydrocortisone / Urinary Calculi / Electrolytes / Hot Temperature / Animals Language: English Journal: Indian J Physiol Pharmacol Year: 1988 Type: Article