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Contraceptive efficacy of Depot Provera jet-injected into the cervix.
Indian J Physiol Pharmacol ; 1991 Jan; 35(1): 21-6
Article in English | IMSEAR | ID: sea-106267
ABSTRACT
Depot-medroxy progesterone acetate (DMPA) was jet deposited into the uterus/cervix of rats, rabbits and rhesus monkeys with the help of a modified jet injection apparatus. Since the drug was delivered under pressure, it was distributed deep into the muscular layers around the place of deposition. After one deposition the drug acted as an effective contraceptive for a period of three months. The merits of this delivery technique are discussed.
Subject(s)
Full text: Available Index: IMSEAR (South-East Asia) Main subject: Progesterone / Rabbits / Rats / Female / Male / Pregnancy / Injections, Jet / Luteinizing Hormone / Cervix Uteri / Medroxyprogesterone Acetate Language: English Journal: Indian J Physiol Pharmacol Year: 1991 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Progesterone / Rabbits / Rats / Female / Male / Pregnancy / Injections, Jet / Luteinizing Hormone / Cervix Uteri / Medroxyprogesterone Acetate Language: English Journal: Indian J Physiol Pharmacol Year: 1991 Type: Article