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Antipyretic activity of diacetyl para-amino phenol.
Indian J Physiol Pharmacol ; 1989 Oct-Dec; 33(4): 216-8
Article in English | IMSEAR | ID: sea-106394
ABSTRACT
Diacetyl para-amino phenol (DAPAP) was generated by interaction between aspirin and paracetamol in a mechanical shaker. It revealed antipyretic activity in albino rats. The antipyretic action was found to be having the same onset of action and duration as that of aspirin. This compound lacked ulcerogenic and analgesic activity. DAPAP therefore may have safety as an antipyretic drug in patients with history of peptic ulcer.
Subject(s)
Full text: Available Index: IMSEAR (South-East Asia) Main subject: Rats / Stomach Ulcer / Female / Male / Anti-Inflammatory Agents, Non-Steroidal / Aminophenols / Analgesics / Animals / Acetaminophen / Mice Language: English Journal: Indian J Physiol Pharmacol Year: 1989 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Rats / Stomach Ulcer / Female / Male / Anti-Inflammatory Agents, Non-Steroidal / Aminophenols / Analgesics / Animals / Acetaminophen / Mice Language: English Journal: Indian J Physiol Pharmacol Year: 1989 Type: Article