Anti-fertility activity and hormonal profile of trans-anethole in rats.
Indian J Physiol Pharmacol
;
1995 Jan; 39(1): 63-7
Article
in English
| IMSEAR
| ID: sea-106585
ABSTRACT
Trans-anethole was studied for antifertility activity in rats at dose levels of 50 mg, 70 mg and 80 mg/kg po. Dose-dependent activity was observed, a 100% anti-implantation activity being achieved at 80 mg/kg, po. The compound showed a significant estrogenic activity and did not possess anti-estrogenic, progestational, anti-progestational, androgenic or anti-androgenic activities. In an earlier study, the compound was found to be safe, its LD50 being more than 3000 mg/kg, po in mice.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Organ Size
/
Prostate
/
Rats
/
Seminal Vesicles
/
Testosterone
/
Female
/
Male
/
Pregnancy
/
Ovariectomy
/
Abortion, Induced
Language:
English
Journal:
Indian J Physiol Pharmacol
Year:
1995
Type:
Article
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