Effect of angiotensin converting enzyme inhibitor (captopril) on gastric ulcer production in pylorus ligated rats.
Indian J Physiol Pharmacol
;
1995 Jul; 39(3): 296-8
Article
in English
| IMSEAR
| ID: sea-106646
ABSTRACT
Intraperitoneal injection of Angiotensin Converting Enzyme inhibitor, captopril, reduced significantly (P < 0.001), the production of gastric ulcers in pylorus-ligated albino rats, compared to the control groups, irrespective of the dose schedule--single or quadruple. In the light of evidence available in the literature, it is reasonable to hypothesise that the anti-ulcer effect of captopril may be mediated through prostaglandins.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Pylorus
/
Rats
/
Stomach Ulcer
/
Female
/
Male
/
Angiotensin-Converting Enzyme Inhibitors
/
Captopril
/
Rats, Wistar
/
Injections, Intraperitoneal
/
Animals
Language:
English
Journal:
Indian J Physiol Pharmacol
Year:
1995
Type:
Article
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