Inhibition of tumour promotion in mice by eugenol.
Indian J Physiol Pharmacol
;
1994 Oct; 38(4): 306-8
Article
in English
| IMSEAR
| ID: sea-106728
ABSTRACT
Number of tumours (papillomas) produced by the application of 7,12-dimethyl benz (a) anthracene as initiator and croton oil promoter in mice were considerably inhibited (84%) by the prior application of eugenol. Moreover, there was considerable decrease in the number of tumour bearing animals and their onset. Eugenol inhibited superoxide formation and lipid peroxidation and the radical scavenging activity may be responsible for its chemopreventive action.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Papilloma
/
Skin Neoplasms
/
Eugenol
/
Superoxides
/
Lipid Peroxides
/
Animals
/
Mice
/
Neoplasms, Experimental
Language:
English
Journal:
Indian J Physiol Pharmacol
Year:
1994
Type:
Article
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