Effect of glucose on stress induced antinociception in normal mice.
Indian J Physiol Pharmacol
;
1998 Jan; 42(1): 131-4
Article
in English
| IMSEAR
| ID: sea-106781
ABSTRACT
Stress induced analgesia has been shown to utilise both non-opioidergic and opioidergic mechanisms. Earlier studies indicate that opiodergic analgesics exhibit corollary changes in blood glucose level. In this study, the changes in blood glucose level by swim induced stress and the influence of exogenous glucose administration on the stress induced antinociception were studied. Stress per se (both 30 sec and 3 min) did not modify the blood glucose level. However, exogenous administration of glucose reversed the stress induced antinociception in both non-opioid and opioid segments. Our results favour a role for glucose in stress induced analgesic activity.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Pain
/
Stress, Psychological
/
Swimming
/
Blood Glucose
/
Male
/
Receptors, Opioid
/
Glucose
/
Analgesia
/
Animals
/
Mice
Language:
English
Journal:
Indian J Physiol Pharmacol
Year:
1998
Type:
Article
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