Morphine analgesia and its modification by drugs altering serotonin (5-HT) and dopamine levels in the brain.
Indian J Physiol Pharmacol
;
1977 Jan-Mar; 21(1): 72-4
Article
in English
| IMSEAR
| ID: sea-106788
ABSTRACT
Morphine analgesia in mice was significantly potentiated by pretreatment with 5-hydroxytryptophan (5-HTP), especially with higher dose of morphine. Morphine analgesia was antagonised by reserpine. With l-dopa it was antogonised when the dose of morphine was minimal but with increased dosage of morphine, there was no significant effect.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Reserpine
/
Levodopa
/
5-Hydroxytryptophan
/
Drug Synergism
/
Analgesia
/
Animals
/
Mice
/
Morphine
Language:
English
Journal:
Indian J Physiol Pharmacol
Year:
1977
Type:
Article
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