Anti-spasmogenic effect of cyproheptadine on guinea-pig ileum.
Indian J Physiol Pharmacol
;
1983 Oct-Dec; 27(4): 342-4
Article
in English
| IMSEAR
| ID: sea-106887
ABSTRACT
Antagonistic activity of cyproheptadine against common spasmogens, like acetylcholine, histamine, serotonin, bradykinin and angiotensin, was studied on isolated guinea-pig ileum. Cyproheptadine produced a reversible antagonism of non-competitive type and was most effective against serotonin. It was less potent against histamine, bradykinin and angiotensin and least potent against acetylcholine.
Full text:
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Index:
IMSEAR (South-East Asia)
Main subject:
Serotonin Antagonists
/
Female
/
Male
/
Angiotensin II
/
Bradykinin
/
Acetylcholine
/
Cyproheptadine
/
Guinea Pigs
/
Histamine Antagonists
/
Ileum
Language:
English
Journal:
Indian J Physiol Pharmacol
Year:
1983
Type:
Article
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