Effect of graded distension of urinary bladder on arterial blood pressure and neurohumors in rabbits.

ABSTRACT

Effect of graded distension of urinary bladder has been observed on the circulating level of catecholamine, cortisol and serotonin along with arterial blood pressure in rabbits. Simultaneously adrenal catecholamine has been also investigated. Similar pattern of increase has been observed in the levels of catecholamine, cortisol, serotonin and arterial blood pressure after bladder distension at 20 ml, 40 ml and 60 ml volumes. On this basis, it may be inferred that there is some role of the vasoconstrictor humors released during bladder distension in pressor response. At the same time, decrease in adrenal catecholamine level also supports this.