Effect of Mn++ on blood sugar level in rats.
Indian J Physiol Pharmacol
;
1982 Jul-Sep; 26(3): 227-30
Article
in English
| IMSEAR
| ID: sea-107056
ABSTRACT
Mn++ produced hypoglycemia in normal rats. The effect was dose-dependent. However, Mn++ did not produce hypoglycemia in alloxan-treated rats. There was a rise in liver glycogen following Mn++ treatment which was correlated with fall in blood sugar at 1 1/2 and 3 hr. There was also increase in the glucose uptake by rat diaphragm upto 47% between 2 and 3 hr. The results suggest that functioning, intact pancreatic beta-cells are necessary for the action of Mn++ and that Mn++ may have a peripheral effect on glucose entry into the cells.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rats
/
Blood Glucose
/
Female
/
Male
/
Diaphragm
/
Diabetes Mellitus, Experimental
/
Glucose
/
Hypoglycemia
/
Liver Glycogen
/
Animals
Language:
English
Journal:
Indian J Physiol Pharmacol
Year:
1982
Type:
Article
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